Methylnaltrexone methobromide: the first peripherally active, centrally inactive opioid receptor-antagonist

Alternate title: 
J2 - Consult Pharm
Secondary title: 
T2 - Consultant Pharmacist
Short title: 
Methylnaltrexone methobromide: the first peripherally active, centrally inactive opioid receptor-antagonist
Authors: 
Guay, David R. P.
Volume: 
24
Start page: 
210-26
Annotations: 
Type A, Priority 5
Date: 
Mar
Year: 
2009
Accession number: 
19555136
Database: 
MEDLINE RCTs
Number: 
M1 - 3
Serial: 
0888-5109
Type of work: 
M3 - Review
ID: 
5121
Notes: 
N1 - Guay DR
Key words: 
Animals
Clinical Trials as Topic
Drug Interactions
Humans
Naltrexone/ae [Adverse Effects]
*Naltrexone/aa [Analogs & Derivatives]
Naltrexone/pk [Pharmacokinetics]
Naltrexone/pd [Pharmacology]
Naltrexone/tu [Therapeutic Use]
*Narcotic Antagonists/pd [Pharmacology]
Quaternary Ammonium Compounds/ae [Adverse Effects]
Quaternary Ammonium Compounds/pk [Pharmacokinetics]
Quaternary Ammonium Compounds/pd [Pharmacology]
Quaternary Ammonium Compounds/tu [Therapeutic Use]
0 (Narcotic Antagonists)
0 (Quaternary Ammonium Compounds)
5S6W795CQM (Naltrexone)
83387-25-1 (methylnaltrexone)
Types of evidence: 
Type A
Priorities of Care: 
Priority 5: Plan and do